If Isaac's health bar is filled with soul hearts, picking up a black heart will replace the topmost soul heart.Īlso know, how do you unlock Isaac's heart?īeat either Satan or Isaac offline, then go to My Games & Apps and delete your save data. Red heart pickups created by item, card, or pill effects can be forced to be spawned as Black or Eternal hearts instead by using the item, card, or pill in a relevant Super Secret Room.
